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Phentermine is a stimulant that is similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.
Phentermine should not be taken by patients with glaucoma, hyperthyroidism, or a history of drug abuse or psychotic illnesses. Phentermine is not recommended in patients with high blood pressure that is not well controlled. Patients on phentermine should have their blood pressure closely followed. Insulin requirements may change in patients on phentermine; alcohol can cause a drug interaction. Abrupt stoppage of the drug can cause withdrawal with fatigue and  depression. Phentermine is potentially addicting. Phentermine is not recommended for patients with symptomatic heart disease including rhythm problems.
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Phentermine is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Phentermine hydrochloride is related chemically and pharmacologically to the amphetamines. Amphetamines and related stimulant drugs have been extensively abused, and the possibility of abuse of Phentermine hydrochloride should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia.
Phentermine may also be used for purposes other than those listed in this medication guide.
Taking phentermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take phentermine with any other diet medications without your doctor's advice.
Phentermine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of phentermine. Phentermine may be habit-forming and should be used only by the person it was prescribed for. Keep track of how many pills have been used from each new bottle of this medicine. Phentermine is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.
Obesity is a chronic disease that affects many people and often requires medical treatment to promote and sustain weight loss. Phentermine, a prescription medication, can be used to assist with the battle of obesity. While most side effects of Phentermine are mild, serious complications involving Phentermine have been reported. Phentermine should only be used by patients who are at increased medical risk because of their obesity. Phentermine should not be used for "cosmetic" weight loss.